A study led by CHU von Angers confirms the benefits of vitamin D against Covid-19

The trace of vitamin D, against Covid-19, does not come out of nowhere. In January 2021, 73 experts and six specialist societies gathered around Dr. Cédric Annweiler, head of the geriatrics department at the CHU of Angers (Maine-et-Loire), and Dr. Jean-Claude Souberbielle, from the Necker Hospital in Paris, underlined its effectiveness in the fight against the virus.

A new study called COVIT-TRIAL, published this Tuesday, May 31, in the scientific journal Plos Medicine puts another brick in the building, confirming the usefulness of vitamin D on top of other standard treatments.

“Very high level of evidence”

Initiated by Pr. Annweiler and piloted by Angevin University Hospital Center, the latter “Shows with very high evidence the benefit of a high dose of vitamin D given within 72 hours of diagnosis of Covid-19 for frail elderly who have contracted the infection.”

Professor Cédric Annweiler, Head of the Department of Geriatrics at the CHU d’Angers. | CATHERINE JOUANNET

Between April and December 2020, 260 patients spread over nine French hospitals and their Ehpads were contacted. It was, as Professor Annweiler points out, “Patients aged 65 and over who have contracted Covid-19 with unfavorable evolutionary criteria”, and “Patients aged 75 and over with Covid-19 without other risk factors”.

Two groups, two different dosages

They were randomly divided into two groups. One receiving a high dose of vitamin D within 72 hours of diagnosis; the other received a significantly lower dose, still within the same time period.

Valuation: “The administration of the high dose of vitamin D […] was responsible for a large and statistically significant reduction in the risk of death as early as the sixth day after the start of treatment. » The authors of the study therefore recommend achieving “As soon as possible, satisfactory vitamin D status in elderly people with Covid-19, using high-dose supplementation once diagnosis is made.”

profit limits

However, if there is a decrease in deaths after 14 days, this benefit is no longer observed after 28 days. The study authors suggest investigating the effect of regular vitamin D supplementation after the initial high dose. They also state that the subject of the study was not the possible preventive effect of vitamin D against the severe symptoms of Covid-19. Useful, but vitamin D is not a panacea.

A study led by CHU von Angers confirms the benefits of vitamin D against Covid-19

Leave a Comment